Research & Development
Science With
a Purpose
- Discovery
- Preclinical
- Phase 1
- Phase 2
- Phase 3
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Neuroscience
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Olanzapine and samidorphan - Schizophrenia or Bipolar I Disorder (pediatric)
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ALKS 2680 - Narcolepsy
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Orexin Agonists - Non-Orphan Indications
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Oncology
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Nemvaleukin alfa* - Platinum-Resistant Ovarian Cancer
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Nemvaleukin alfa - Mucosal Melanoma
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IL-12
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IL-18
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Last updated: July 2023
Scientific Platforms
As we look forward, we are taking a “bedside to bench” approach to R&D -扭转典型的思维过程，从现实世界开始, 当十大正规网博平台寻求在神经科学和肿瘤学领域开发新的治疗方法时，未满足的患者需求告知十大正规网博平台的工作. 十大正规网博平台的药物开发工作集中在两个具有广泛潜力的科研平台上.
Synaptic Dysfunction
Our synaptic dysfunction platform is designed to improve the structure, function and environment of synapses. 突触完整性和功能的改善有可能减缓进展, and preserve cognitive and functional abilities, in multiple neurological and psychiatric diseases.
Immune Modulation in Oncology
十大正规网博平台的免疫肿瘤学平台旨在利用免疫系统的力量来对抗癌症. 十大正规网博平台正在开发新的基于细胞因子的疗法，旨在提高肿瘤细胞对免疫系统的可见度, 增加CD8+ T和自然杀伤细胞的肿瘤杀伤潜能, and remove suppressive signals in the tumor microenvironment. Nemvaleukin alfa, our most advanced investigational immunotherapy candidate, was developed using this platform.
Long-Acting Technologies
十大正规网博平台的长效注射技术能够在特定的时间内以可控的速率将小分子和复杂的大分子逐渐释放到体内. These include Medisorb®, LinkeRx® and NanoCrystal®.
Oral Controlled-Release Technologies
Our broad array of customized, solid-oral dosage technologies, including oral delayed-release, extended-release, immediate-release, 脉冲释放和定时递送使十大正规网博平台能够定制特定的药物释放概况和剂型.
Protein Engineering
十大正规网博平台正在利用现有的蛋白质工程平台开发具有抗癌潜力的新型细胞因子.
Investigator Sponsored Studies
十大正规网博平台寻求支持由独立临床医生和科学家设计和实施的研究者研究. 自2008年十大正规网博平台的研究者赞助研究(ISS)项目开始以来, we have supported more than 40 clinical trials.
Alkermes Pathways Research Awards®
Alkermes Pathways Research Awards® 是否有一个竞争性的资助项目，为下一代研究人员在前线工作，以提高对神经科学领域疾病状态的理解和认识.
As a researcher, 我所做的最令人兴奋的事情之一就是提出能够长期影响患者的想法. My job is to figure out how we can make the biggest impact.
Laura Tan,
Research Scientist
Clinical Trials
Alkermes致力于研究和开发创新药物，以帮助解决患者及其家属未满足的需求. Clinical trials are a critical part of this process, 在此期间，十大正规网博平台寻求确定研究药物的安全性和有效性，或进一步了解已上市药物.
有关正在进行的使用Alkermes已上市或研究药物的临床试验的信息, please consult the National Institutes of Health website, www.clinicaltrials.gov, which contains a searchable database.